Muayyad Al-Ubaidi
John & Rebecca Moores ProfessorDr. Muayyad R. Al-Ubaidi is a tenured professor in the Department of Biomedical Engineering. Dr. Al-Ubaidi has a solid track record in his field of research. He was the first to publish the genomic sequence of mouse rhodopsin, which served as a stepping-stone for others in the production of mouse models of rhodopsin-based inherited retinal diseases. Utilizing his training in mouse transgenesis, he has been very active in the production of transgenic models of inherited retinal disease. He is currently funded by awards from the National Institute of Health and the Foundation Fighting Blindness. His current research focuses on therapeutic approaches to retinal degenerative diseases caused by mutations in the Prph2 protein.
Dr. Al-Ubaidi is a leader in mouse transgenesis. He has been very active in the production of transgenic models of inherited retinal disease.
Selected Publications
- Zhao X, Naash MI, Al-Ubaidi MR. Riboflavin, Retbindin, and Riboflavin Transporters in the Retina Adv Exp Med Biol. 2025;1468:471-475. doi: 10.1007/978-3-031-76550-6_77. PMID: 39930240 Review.
- Rutan Woods CT, Makia MS, Lewis TR, Crane R, Zeibak S, Yu P, Kakakhel M, Castillo CM, Arshavsky VY, Naash MI, Al-Ubaidi MR. Downregulation of rhodopsin is an effective therapeutic strategy in ameliorating peripherin-2-associated inherited retinal disorders. Nat Commun. 2024 Jun 4;15(1):4756. doi: 10.1038/s41467-024-48846-5. PMID: 38834544
- Crane R, Makia MS, Zeibak S, Tebbe L, Ikele L, Woods CR, Conley SM, Acharya G, Naash MI, Al-Ubaidi MR. Effective intravitreal gene delivery to retinal pigment epithelium with hyaluronic acid nanospheres. Mol Ther Nucleic Acids. 2024 May 20;35(2):102222. doi: 10.1016/j.omtn.2024.102222. eCollection 2024 Jun 11. PMID: 38868364
- Ikelle L, Naash MI, Al-Ubaidi MR. Modulation of SOD3 Levels Is Detrimental to Retinal Homeostasis Antioxidants (Basel). 2021 Oct 12;10(10):1595. doi: 10.3390/antiox10101595. PMID: 3467972